Department of Chemistry
A comprehensive research resource for state-of-the-art nuclear magnetic resonance (NMR) has been established at the College of Staten Island. It consists of three NMR spectrometers (600, 300 and 200 MHz) and a number of SUN and SGI UNIX workstations. Directed by Professors Ruth Stark and Fred Naider, this facility is primarily utilized by the researchers at the Department of Chemistry. In addition, it is made available to academic, industrial, and governmental researchers. The facility is managed by Dr. Hsin Wang.
UNITYplus 300 MHz
UNITY 200 MHz
NMR related Projects at the Department of Chemistry include research works in the following groups:
Prof. James Batteas' Group
Prof. Probal Bannerjee's Group
Prof. Fred Naider's Group
Prof. Ruth E. Stark's Group
Typical internal CUNY projects that rely on these advanced NMR facilities span the areas of rational drug design, nutritional therapy, protein structure and folding, plant-derived medicines, crop protection, and polymer manufacturing. Staff members at the CUNY Center for Applied Biomedicine and Biotechnology (CABB) are also working to optimize protocols for structure determination of complex biological molecules and intractable natural products. Underlying both internal and collaborative studies at the NMR Facility is the expectation that knowledge of the relevant molecular structures will yield practical functional information in the areas of human physiology, food production, and advanced materials design.
NMR takes scientific researchers to the level of individual molecules in their efforts to address key problems in biomedicine and chemical technology. Through scientific collaborations and with the benefit of computer networking, the CUNY facilities are used and supported financially by researchers at numerous academic, governmental, and industrial institutions. For instance, chemists at CUNY CSI and Monsanto Company are conducting joint 13C and 2H solid-state NMR experiments to understand the waterproofing and antifungal functions of the skin of plants. In partnership with Staten Islands NYS Institute for Basic Research in Developmental Disabilities, these CUNY scientists are using high-field two-dimensional NMR to develop a molecular basis for the action of anticonvulsant drugs. CUNY CSI researchers are also using 1H and 13C NMR along with their counterparts at Hoechst-Celanese to characterize materials used industrially in packaging films and oil additives. At Hunter College, New York Citys Innovir Laboratories is monitoring the modification of polynucleotides with 31P NMR. Diatide Corporation is carrying out one- and two-dimensional NMR experiments to examine the molecular structure and metal binding sites of radiolabeled peptide drug candidates.
Faculty in Charge
Dr. Ruth E. Stark, College of Staten Island, Tel: (718) 982-3894 email: firstname.lastname@example.org
Dr. Fred Naider, College of Staten Island, Tel: (718) 982-3896 email: email@example.com
Dr. Hsin Wang, College of Staten Island, Tel: (718) 982-3809 email: firstname.lastname@example.org